PREDIMED’s 2013 report was retracted for randomization problems and republished in 2018 with corrected analyses. The Mediterranean pattern still reduced major cardiovascular events versus a low-fat advice control.
Research
Strong evidence
PREDIMED Mediterranean diet (2018 republication)
Primary prevention trial of Mediterranean diets plus olive oil or nuts.
Details
- Authors
- Estruch R, Ros E, Salas-Salvadó J, et al.
- Publication
- New England Journal of Medicine
- Published
- 2018
- Abstract
- In a multicenter trial, Mediterranean diets supplemented with extra-virgin olive oil or nuts reduced the rate of major cardiovascular events compared with a control diet among high-risk persons.
- Full text
- https://doi.org/10.1056/NEJMoa1800389
- Key findings
- Both Mediterranean arms lowered the composite of myocardial infarction, stroke, or cardiovascular death versus control after protocol corrections.
- Methodology
- Multicenter randomized trial with reanalyzed intention-to-treat estimates after identified randomization irregularities.
Editorial rating ★ 4.6
Use the 2018 paper, not the retracted one. Food pattern still wins.
Reviews
No reviews yet. Be the first to share your experience.