Randomized work showing urolithin A can improve muscle endurance and mitochondrial biomarkers in older adults.
Research
Moderate evidence
Urolithin A and muscle endurance
Human trial often cited for Mitopure.
Details
- Authors
- Singh et al. and related groups
- Publication
- JAMA Network Open / related journals
- Published
- 2019–2022 cluster
- Abstract
- Urolithin A supplementation improved endurance-related outcomes versus placebo in selected adult groups.
- Full text
- https://pubmed.ncbi.nlm.nih.gov
- Key findings
- Mitochondrial gene expression and 6-minute walk / endurance measures improved in some cohorts.
- Methodology
- Randomized, placebo-controlled supplementation.
Editorial rating ★ 4.4
One of the cleaner supplement papers in the longevity aisle.
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