Sutton and Peterson’s crossover trial fed men with prediabetes enough to hold weight. Eating in a 6-hour early window still improved insulin sensitivity, blood pressure, and oxidative-stress markers versus a 12-hour schedule.
Research
Moderate evidence
Early time-restricted feeding (Sutton 2018)
eTRF improved insulin and blood pressure without weight loss.
Details
- Authors
- Sutton EF, Beyl R, Early KS, Cefalu WT, Ravussin E, Peterson CM
- Publication
- Cell Metabolism
- Published
- 2018
- Abstract
- In a supervised crossover feeding study, early time-restricted feeding (6-hour window, dinner before 3 p.m.) improved insulin sensitivity, β-cell responsiveness, blood pressure, oxidative stress, and appetite without weight loss.
- Key findings
- Cardiometabolic improvements occurred even when calories were matched to prevent weight loss; sample was eight men with prediabetes.
- Methodology
- Randomized crossover controlled-feeding trial, 5 weeks per schedule.
Editorial rating ★ 4.5
Small, elegant, and often oversold. The clock matters, but so does what is on the plate.
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