Supplements Limited evidence

Resveratrol

The red-wine polyphenol that did not become a drug.

Resveratrol had a sirtuin moment and then a quieter decade. Bioavailability is poor, doses in bottles rarely match the mouse papers, and wine is still wine. If you want polyphenols, food is less theatrical and cheaper.

How to use

150–500 mg with a meal if you insist on a capsule.

Details

Ingredients
Trans-resveratrol
Benefits
Polyphenol exposure
Dosage
150–500 mg
When to take
With food
Side effects
GI upset; possible drug interactions at high dose.
Scientific evidence
Human metabolic and longevity outcomes have not matched early hype.
Form
Capsule
Third-party tested
Yes

Editorial rating ★ 3.2

Over-promised. Keep it optional and ignore the “liquid youth” ads.

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