Supplements Limited evidence

5-HTP

Serotonin precursor. Not a casual mood candy.

5-HTP converts toward serotonin. That is why it shows up in sleep and mood stacks — and why it is a bad idea next to SSRIs, MAOIs, or other serotonergic drugs. If mood is the problem, a clinician beats a capsule.

How to use

50–100 mg in the evening only if you are not on serotonergic medication.

Details

Ingredients
5-hydroxytryptophan
Benefits
Sleep onset (some users), Mood support (mixed)
Dosage
50–100 mg
When to take
Evening, Before bed
Side effects
Nausea, vivid dreams. Serotonin syndrome risk with many psychiatric meds.
Scientific evidence
Small trials on sleep and appetite; safety is dominated by drug-interaction risk.
Form
Capsule
Third-party tested
Yes

Editorial rating ★ 3.3

Real biochemistry, real interaction risk. Default to no if you take antidepressants.

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